Polyvinylpyrrolidone K30 CAS：9003-39-8 CAS NO.9003-39-8

 PVP K30

1. Superior Product Quality

• High Purity & Purity Consistency: Manufactured under strict GMP standards, PVP K30 features ultra-low impurity levels (e.g., residual monomers, heavy metals), ensuring compliance with international pharmacopoeias (USP, EP, CP, JP).
• Uniform Molecular Weight Distribution: Precise control over polymerization processes guarantees consistent molecular weight (K-value 28–32), leading to stable viscosity and binding performance in pharmaceutical formulations.
• Excellent Stability: Resistant to thermal degradation and chemical interference, making it suitable for heat-sensitive drugs and long-term storage.
• Biocompatibility & Safety: Non-toxic, non-irritating, and low-allergenic, with a proven safety profile for oral, topical, and parenteral applications.

2. Advanced Manufacturing Technology

• Proprietary Polymerization Processes: Adopts innovative solution polymerization or bulk polymerization techniques to optimize molecular structure and reduce production impurities.
• High-Precision Control Systems: Automated production lines with real-time monitoring of temperature, pressure, and reaction kinetics ensure batch-to-batch consistency.
• Green Production Practices: Employs environmentally friendly solvents and energy-efficient processes, aligning with global sustainability standards.
• R&D Capabilities: Backed by a team of polymer chemistry experts, capable of customizing PVP K30 for specific application needs (e.g., modified surface activity for targeted drug delivery).

3. Competitive Pricing Strategy

• Economies of Scale: Large-scale production facilities enable cost-efficient manufacturing, offering competitive prices without compromising quality.
• Transparent Cost Structure: Clear pricing models based on order volume, supporting flexible procurement for both small-scale R&D and large-scale commercial production.
• Long-Term Partnership Discounts: Exclusive pricing agreements for long-term clients, reducing total cost of ownership for pharmaceutical manufacturers.
• Value-Added Cost Efficiency: High binding efficiency minimizes usage rates, lowering formulation costs compared to alternative excipients.

4. Comprehensive Service Support

• Technical Expertise & Consultation: Dedicated technical teams provide formulation guidance, troubleshooting, and compatibility testing for clients.
• Rapid Response & Customization: 24/7 customer service for urgent inquiries, plus tailored solutions for special requirements (e.g., sterile-grade PVP K30 for injectables).
• Regulatory Compliance Assistance: Support in preparing DMFs, CE certifications, and local regulatory filings to facilitate global market access.
• Reliable Supply Chain: Robust logistics networks ensure on-time delivery, with contingency plans to prevent supply disruptions (e.g., redundant raw material sources).
• After-Sales Support: Post-installation training, performance tracking, and continuous process optimization to enhance client operational efficiency.

Polyvinylpyrrolidone K30 (PVP K30) Product Introduction

1. COA Information (Certificate of Analysis)

Chemical Name: Polyvinylpyrrolidone K30

Molecular Formula: (C?H?NO)

CAS No. : 9003-39-8

Molecular Weight: ~38,000 Da

Appearance: White to off-white free-flowing powder with hygroscopic property

Key Quality Indicators:

• K-Value: 27.0–32.0 (indicates molecular weight consistency)

• pH (1% Aqueous Solution): 3.0–7.0

• Moisture Content: ≤5.0%

• Residual Monomer (N-vinylpyrrolidone): ≤0.1%

• Heavy Metals: ≤10 ppm

• Nitrogen Content: 11.5%–12.8% (anhydrous basis)

• Aldehydes (as acetaldehyde): ≤0.05%

• Sulfated Ash: ≤0.1%

Standards Compliance:

Comply with USP, EP, CP, and JP pharmacopoeias, manufactured under GMP-certified facilities

2. Product Applications

PVP K30 serves as a versatile excipient and functional additive across multiple industries:

Pharmaceutical Industry

• Binder for Tablets & Granules: Enhances particle aggregation and tablet hardness, suitable for direct compression or wet granulation

• Solubilizer for Injectables: Improves solubility of poorly water-soluble drugs via complexation

• Stabilizer for Sensitive Formulations: Protects enzymes and heat-labile drugs from degradation

• Film Former in Ophthalmic Solutions: Forms a protective layer on ocular surfaces with excellent biocompatibility

• Disinfectant Component: Combined with iodine to form PVP-I, a broad-spectrum antiseptic

Other Industries

• Cosmetics: Thickener and film former in shampoos, toothpastes, and contact lens solutions

• Food & Beverage: Fining agent for white wine and beer, binder in food coatings

• Technical Applications: Additive for batteries, ceramics, inks, and inkjet paper to improve processability

3. Supply Capacity & Manufacturing Advantages

Supply Capability

• Annual Production: 20,000 metric tons, supported by large-scale reactors and automated production lines

• Lead Time: 1–3 weeks for standard orders, with flexible batch sizes from 1 kg (sample) to bulk shipments

• Packaging Options: 25 kg drums, custom packaging available (e.g., sterile-grade bags for pharmaceutical use)

Process Advantages

• Proprietary Polymerization Technology:

Adopts solution polymerization with precise temperature (±0.5°C) and pressure control, minimizing residual monomers and ensuring narrow molecular weight distribution

• Green Manufacturing:

Employs eco-friendly solvents and energy-efficient processes, reducing carbon footprint by 30% compared to conventional methods

• Quality Control System:

Real-time monitoring of key process parameters (e.g., reaction kinetics, viscosity) via HPLC and FTIR, ensuring batch-to-batch consistency

• Regulatory Support:

Pre-certified DMF files, assistance with local registrations (e.g., CE, FDA), and annual GMP audits

4. Visual Assets for Company Presentation

• Sample & Packaging Images:

Showcases white powder samples in 25 kg drums (with tamper-evident seals) and 1 kg aluminum foil bags for R&D purposes